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"Tobacco-specific nitrosamines, some of the chemical compounds in thirdhand smoke, are among the most potent carcinogens there are." A January paper in PLOS ONE that used mice to assess the health hazards highlighted the knowledge gap: Although the potential risks attributed to [thirdhand smoke] exposure are increasing, virtually nothing is known about the specific health implications of acute or cumulative exposure

Additionally, smoking impairs blood flow to the mouth and gums, hindering their ability to fight off infection and repair damage

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doi:10.1038/s41562-021-01202-9

The WHO reports that secondhand smoke causes serious cardiovascular and respiratory diseases, including lung cancer, and kills approximately 1.6 million people prematurely every year globally