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This can show up in a number of different ways including: Not feeling as high as you did when you first started Needing to use more frequently Needing higher potency (like using concentrates rather than flower) Using a higher dose or quantity to feel the same high If you experience symptoms of tolerance, you may consider taking a tolerance break (t-break) to help reduce your tolerance and cravings

Fong GT, Hammond D, Jiang Y, et al

However, GIoU, DIoU, and CIoU are all extensions of IoU, commonly used in loss functions

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The preliminary data is disconcerting, said Andre Macedo Dias, MD, a cardiologist with Baptist Heart Specialists

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