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CHANTIX has also been studied in postmarketing trials including (1) a trial conducted in patients with chronic obstructive pulmonary disease (COPD), (2) a trial conducted in generally healthy patients (similar to those in the premarketing studies) in which they were allowed to select a quit date between days 8 and 35 of treatment ("alternative quit date instruction trial"), (3) a trial conducted in patients who did not succeed in stopping smoking during prior CHANTIX therapy, or who relapsed after treatment ("re-treatment trial"), (4) a trial conducted in patients with stable cardiovascular disease, (5) a trial conducted in patients with stable schizophrenia or schizoaffective disorder, (6) a trial conducted in patients with major depressive disorder, (7) a postmarketing neuropsychiatric safety outcome trial in patients without or with a history of psychiatric disorder, (8) a non-treatment extension of the postmarketing neuropsychiatric safety outcome trial that assessed CV safety, (9) a trial in patients who were not able or willing to quit abruptly and who were instructed to quit gradually ("gradual approach to quitting smoking trial")

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Basically, Big Tobacco is dropping major bucks to attract a new generation of smokers and lure customers away from smaller competitors, all while burnishing their corporate reputations

District Judge Gladys Kessler wrote in the court's opinion that the companies had engaged in "massive wrongdoing" that caused, "a staggering number of deaths per year, an immeasurable amount of human suffering and economic loss, and a profound burden on our national health care system." The lawsuit alleged that the tobacco companies had engaged in racketeering and conspiracy to hide the truth about health conditions caused by smoking and had purposely designed cigarettes that were highly addictive

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