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With more than 16 million people in the U.S
Infamously, already 30 years ago, the industry claimed that I believe nicotine is not addictive
Vickerman et al 80 found that 31% of quit-line callers surveyed 7 months after enrollment reported that they had ever tried e-cigarettes
Large clusters of puffs in relatively quick succession result in a near-bolus dose of nicotine, rapid rise in blood nicotine levels, and likely greater nicotine-related effects (positive reinforcement)
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