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The nondrinker subgroup had the smallest sample size of the subgroups, so replication in larger samples is needed before firm conclusions may be drawn about whether drinking status should be taken into account when considering naltrexone as an adjunct smoking cessation treatment in patients who have not responded to approved first-line pharmacotherapies

While the authors acknowledge this shortcoming in the study design, the omission severely skews the conclusion

A White House spokeswoman said Monday that the administration had no update on the matter

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Quitting smoking not only benefits overall health but also plays a significant role in preventing the onset of pancreatic cancer

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