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This is the second of two articles on smoking cessation

Supporters say dissolvables could help smokers step down from their nicotine dependence on cigarettes

In hepatocytes that induce fibrosis, heavy smokers accumulate excess iron and promote HCC development

One primary endogenous source of ROS is the enzyme NADPH oxidase (NOX), which catalyzes the transfer of electrons from cytoplasmic NADPH to molecular oxygen, resulting in the formation of superoxide anions that react with NO to form peroxynitrite, a highly unstable species that can generate further ROS [21,22]

Am J Public Health 97 , 19811991 (2007)