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In a recent survey, adolescents between 13 and 18 years of age were found to vary in their perceived harm of electronic cigarettes based on socioeconomic status, ethnic background, and parental educational attainment (23)

You might not notice those lines at first, but the more you smoke and the longer you do it, the more noticeable they become

(63), may reflect differences in study design, sample size, or measurement techniques

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For instance, chronic inflammation, characterized by heightened TNF- and IL-6, can exacerbate oxidative stress, leading to increased ROS production and mitochondrial dysfunction [45,46,50,53]