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The p53 target p21 competes with Keap1 for Nrf2 binding, resulting ultimately in a stable and activated Nrf2 that upregulates the expression of several genes through binding to AREs [54]

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I think [its rooted] in a bit of my past also, growing up in Camarines Sur as a panganay (eldest child) to my two male siblings, I am the one in charge of taking them to barbershops