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Smoking can impair sperm production and motility, leading to difficulties in achieving pregnancy

Despite these setbacks

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Over time, the confluence of these effects can cause damage to the lining itself and even potentially to the DNA of the epithelial cells

Mice genetically deficient in miR - 223 displayed markedly exacerbated experimentally induced colitis, hyperactivated NLRP3 , and IL - 1 release, while mice with overexpressed miR-223 displayed the opposite effects [185], suggesting that miR - 223 represents a novel target for reducing the inflammatory response

Smoking affects the entire body, including every part of your digestive tract