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The chemical structure of -blockers is of organic compounds consisting of an aryloxypropanolamine side chain to which an aromatic or heteroaromatic ring is attached (Bekhradnia and Ebrahimzadeh, 2012)

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Because of its widespread use as a food additive and other industrial uses, PG was subjected to standard in vivo toxicological assays many years ago, and these studies, coupled with the relative lack of human evidence of toxicity of PG from its use as a food additive, form the basis for FDAs listing of PG as GRAS

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doi: 10.1016/s0092-8674(00)80937-x