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Similarly, mice with p53 mutations that impair the transcriptional activation of p21 , Puma and Noxa , but retain the ability to induce the transcription of certain other p53 target genes, also do not develop tumours spontaneously [38]
Sun YV, Smith AK, Conneely KN, Chang Q, Li W, Lazarus A, et al
14 : 393400 McCoy G, Wynder E
Survival in operable non-small-cell lung cancer: role of p53 mutations, tobacco smoking and asbestos exposure
