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Lobelia ( Lobelia inflata ) Traditional use: Smoking cessation aid and respiratory stimulant in Eclectic herbal medicine

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Hence, one might postulate that given the potentially large effect size of the aforementioned factors associated with both smoking status and IBD, that the magnitude of any direct mechanistic or toxic effect of smoking constituents on the intestinal milieu or treatment(s) might in fact be dwarfed by these cofactors, as represented in Fig