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Participants were blinded as to what stimulus they were receiving, and when the smoke bolus was to be delivered

Shisha may represent lower harm because it is more commonly used socially and at special events rather than smoked every day, or it could represent a more severe problem as the cooler smoke is more pleasurable to inhale so held in the lungs for longer, causing more damage

Their stress-response systems dont behave precisely like those without trauma

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Ideally, management of nicotine addiction combines medications to suppress cravings with counseling to help patients reprogram their behavior, just like treatments for high blood pressure and type 2 diabetes often combine medication with counseling for stress management or behavior change