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15 , 16 With long-term exposure to nicotine, some nicotinic cholinergic receptors become desensitized but some do not

If, or when, it wants to revisit the proposal the FDA should first seek out and listen to doctors about the negative health implications of pushing smokeless tobacco users toward cigarettes, from scientists and manufacturers describing whether or not it is even possible to comply with the proposal, and from workers who could lose their jobs as a result of the rule.

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