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The homologous genes involved in nicotine catabolism, such as cup , ponh , kdh L, TR 2, kdh M, kdh S, nit , ndh L, ndh S, ndh M, cox G, dhph , pkc , mox , TR 1, 6hlno have been identified in Nocardioides sp

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However, a range of negative consequences follows from allowing a large illicit market to thrive: Illicit products are unregulated and may be of poor quality, even dangerous

A quarter of the tobacco-growers farm less than 1 ha

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New York Mayor Michael Bloomberg donated $500,000 to support the 2012 initiative, which was heavily outspent by tobacco interests and narrowly defeated