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In animal smoke exposure models, NLRP3 or GSDMD gene knockout mice exhibit reduced pulmonary inflammatory infiltration, decreased airway remodeling, and structural damage, further supporting the pathogenic role of pyroptosis in COPD progression at the in vivo level (96, 97)
(2023) 11:e48253

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Plasma sE-cadherin and the plasma sE-cadherin/sVE-cadherin ratio are potential biomarkers for chronic obstructive pulmonary disease

[10] Brandt, A.M
