did frank zappa smoke cigarettes This is my favorite pic of Frank. He looks so happy here. : r/Zappa Frank Zappa – Stompbox Book

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Nicotine is an addictive chemical that affects neurotransmitters in the brain, altering the activity of chemicals such as: dopamine serotonin acetylcholine norepinephrine These chemicals affect mood, memory, and feelings of pleasure

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While nicotine is not a carcinogen by itself, it is habit-forming, addictive, and is responsible for keeping people hooked, increasing their cigarette consumption exponentially with time