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TRPM3 is a similar ion channel that is activated by noxious heat as well as pregnenolone sulfate

Licensed under CC BY 4.0 ( No endorsement implied.* TMAO and Type 2 Diabetes: Insulin Resistance and Inflammation Type 2 Diabetes (T2D) patients tend to have higher TMAO levels, linking this gut microbial metabolite to insulin resistance and metabolic risk

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