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revealed that GPX4 overexpression prevents basophilic leukemia cells in mice from death caused by oxidative damage (Imai et al., 1996), thus, theoretically, GPX4 overexpression could make cells resistant to oxidative stress-induced ferroptosis

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Silicosis has imposed a significant economic burden on society due to the absence of effective treatments ( Although H 2 has been applied in clinical practice (Ohsawa indicated that hydrogen can reduce cytotoxic oxygen radicals ( 2 to the antioxidant effect of silicosis