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Description
Such phosphorylation leads to the blockade of the tyrosine residues in IRSs, to which the insulin and IGF-1 receptors phosphorylate to activate IRSs and consequently commence the signalling cascade [185, 192], as comprehensively discussed above
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[DOI] [PMC free article] [PubMed] [Google Scholar] 268.Puig M., Shubow S
