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Tramutola A, Triplett JC, Di Domenico F, Niedowicz DM, Murphy MP, Coccia R, Perluigi M, Butterfield DA

Diabetes Care 29 , 20642071 (2006)

Significantly reduced ATP levels and reduced activity in oxidative phosphorylation complexes I and IV of the electron transport chain (ETC) in SZ patient-derived neurons with 22q11.2DS have also been observed [77]

It is known that improper DNA packaging can increase the vulnerability of DNA to reactive oxygen species (ROS) that DNA is exposed to, which can cause telomere disruption in mature sperm