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N Engl J Med 317:16251629
Can Vitamin B12 Deficiency Cause Joint Pain
The mitochondrial AST enzyme is encoded by the GOT2 gene which is located on chromosome 16q21 and is composed of 10 exons that generate two alternatively spliced mRNAs encoding precursor proteins of 430 amino acids (isoform 1) and 387 amino acids (isoform 2)
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For example, compared with the SPF control, GF Swiss Webster, National Institutes of Health Swiss, and Naval Medical Research Institute mice showed decreased anxiety-like behavior
