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however, the majority have failed clinical trials due to adverse side effects, which typically include increased blood lipid levels and/or fatty liver, suggesting that prolonged and chronic activation of hepatic GCK adversely affects hepatic lipid metabolism (69, 84)

( 10.1038/s41598-019-40638-y) [DOI] [PMC free article] [PubMed] [Google Scholar] 37

Intervention Patients in the LC group received 4 g/d L-carnitine infusion (2 g, twice a day) (Lanling Pharmaceutical CO., LTD, Changzhou, China) from the beginning of the pre-fasting day at 9 am and 4 pm to the last day of fasting

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