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Endothelial dysfunction precedes the development of atherosclerosis and hypertension, the main risk factors for myocardial infarction and heart failure (Scioli et al
Tsurusaki, S

J Pept Res 2005

Both products, along with 3-deoxyglucosone (or Amadori product), serve as precursors for the formation of AGEs, which react with elements of the extracellular matrix (ECM), leading to AGE production

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Mondal BC, Paria N, Majumdar S, Chandra S, Mukhopadhyay A, Chaudhuri U et al
