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A metabolomic investigation further showed that d-carnitine feeding increased glycolysis, protein metabolism and activity of the tricarboxylic acid cycle and oxidative phosphorylation

It is reported that the expression of CAC is up-regulated by statins, fibrates and retinoic acid

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A similar effect has been observed in patients aged 74 to 79 years with multi-infarct dementia [143]

Another investigation revealed that administering nanoceria at postnatal day 28 in Vldlr null mice led to the suppression of various pro-inflammatory cytokines and pro-angiogenic factors, such as Vegfa, Fgf1, and Fgf2, while upregulating anti-angiogenic genes within one week [157]

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