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Effect of opicapone on levodopa pharmacokinetics in patients with fluctuating Parkinsons disease

Mar 29 2012;366(13):1181-1189
Int J Pharm Clin Res

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In each trial, the rat was placed into the water from one of four cardinal directions in a pseudorandom order and allowed up to 120 seconds to locate the platform

By evening, cortisol is at its nadir
