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Svendahl L, Underwood LE: Fasting increases serum total cholesterol, LDL cholesterol, and apolipoprotein B in healthy, nonobese humans

Metformin may increase the risk of lactic acidosis, so starting the treatment with this agent needs to be preceded by careful analysis of renal, liver or heart function of the patient

Some researchers have even speculated that increased intestinal permeability is a cause or contributing factor to food allergies and adverse food reactions

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