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While there arent currently many prescription medications that directly affect glutamate, there are several companies investigating its potential for treating severe treatment-resistant depression, substance abuse, and obsessive-compulsive disorder

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2021;13(4) doi: 10.3390/nu13041154

The question, then, is are supplemental forms of carnitine, choline, etc

Use of guidelines improves the neurological outcome in glutaric aciduria type I

however, current outcome measures may be unable to identify sensitively subtle changes to demonstrate a significant effect