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Accumulating evidence highlights that mitochondrial reactive oxygen species (ROS) imbalance is not merely a byproduct of tissue damage but acts as a central pathological driver, initiating and sustaining skeletal muscle wasting

Nat Rev Dis Primers (2020) 6(1):52

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Indeed, histamine can act as a modulator of release of the aforementioned implicated neurotransmitters (Molina-Hernndez et al., 2012)
