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The combination of high thermodynamic but low kinetic stability is one of the main features of the metal-MT complexes, which bind the metals very tightly but a part of the metal ions is easily exchanged for other proteins (Hassinen et al., 2011)

doi: 10.3390/molecules23030549 [DOI] [PMC free article] [PubMed] [Google Scholar] 101

DG the PG is accurate, and also a nickname you give a second-grader

Direct delivery and absorption also aid in preventing unwanted system effects

The main therapeutic agents targeting HD-associated ferroptosis include DFO and Fer-1

Interestingly, electroacupuncture treatment can relieve neuropathic pain following nerve injury by activating the IGF-1 pathway[88]