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ABSTRACT There is significant evidence that the pathogenesis of several neurodegenerative diseases, including Parkinsons disease, Alzheimers disease, Friedreichs ataxia and amyotrophic lateral sclerosis, may involve the generation of reactive oxygen species and mitochondrial dysfunction

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Inhibition of key glycolysis enzymes, multidrug resistance gene-1 (MDR-1) and PKM-2 significantly increased the sensitivity of ovarian cancer cells to paclitaxel (252)

Innate vascular failure by application of neuroleptics, amphetamine, and domperidone rapidly induced severe occlusion/occlusion-like syndromes in rats and stable gastric pentadecapeptide BPC 157 as therapy