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Among the possible serious complications are anterior uveitis and (pigmentary) glaucoma

doi:10.1073/pnas.0400195101

Although the lesions are usually benign, transformation to malignant melanoma has been reported

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10.1016/S0140-6736(85)91481-3 Ohtani Y, Endo F, Matsuda I: Carnitine deficiency and hyperammonemia associated with valproic acid therapy