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doi: 10.3390/genes13020205

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discussion 495

In developed countries, the most important route of HCV transmission is intravenous drug abuse, whereas in resource-poor countries invasive procedures or injection-based therapies with contaminated instruments are the predominant source of new infections[3]

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While insufficient choline intake is linked to liver dysfunction, neurodegeneration, and muscle damage, excessive intake primarily results in mild cholinergic side effects such as sweating, diarrhea, hypotension, and fishy body odor, with a tolerable upper intake level of 3.5 g/day in adult individuals (5759)