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J Cell Physiol Acetaminophen sensitizing erastin-induced ferroptosis via modulation of Nrf2/heme oxygenase-1 signaling pathway in non-small-cell lung cancer

Antioxidants 10 , 606

The enhanced susceptibility of CF AECs to ferroptosis is consistent with the published literature suggesting that iron homeostasis is disrupted in the CF lung [20, 21]

In a separate set of experiments, we also tested the effect of the SSAO inhibitor LJP-1207 and the reversible MAO-B inhibitor safinamide in the following arrangement: (1) Control (SAL), (2) Kanamycin (800 mg/kg), (3) Kanamycin (800 mg/kg) plus LJP-1207 (20 mg/kg), (4) Kanamycin (800 mg/kg) plus safinamide (10 mg/kg)

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Leverenz J
