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Bone marrow biopsy showed a hypercellular bone marrow with flow cytometry showing an abnormal plasma cell population (1520% plasma cells by immunohistochemistry), consistent with POEMS syndrome

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The crucial question is how much of each metal is accessible to nascent metalloproteins and how tightly must a protein (such as CbiK) bind in order to compete for each of these ions

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Your body can absorb only so much

Oral supplements and oral vitamin B12 are also effective methods of supplementation