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While supplements may be appropriate for some people, they may not be safe for everyone, and they could interact with other medications a person is taking

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344,345 Notably, conjugated linoleic acid appears to be the preferred substrate for these reactions 160 and mechanisms associated with NO 2 production are increased during inflammation and metabolic stress with both 9( E ),11( E )-9-NODE and 9( E ),11( E )-12-NODE being produced