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Rigorous efficacy and dose-ranging studies are lacking but are warranted in order to establish evidence-based use and dosing guidelines

Baker HWG, et al

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Dietary choline supplementation effectively suppressed airway inflammation in an allergen-induced mouse model of airway hyperreactivity by reducing eosinophil accumulation and eosinophilic peroxidase activity in bronchoalveolar lavage fluid, likely through nicotinic acetylcholine receptor activation via the cholinergic anti-inflammatory pathway (93)

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