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2001;20(Suppl 2):106118
Notably, a single mtDNA mutation has minimal impact on the physiological phenotype, and it is only when the number of mutant mtDNAs exceeds a threshold that cellular function is compromised
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These dimers undergo conformational changes and gradually aggregate into nucleus-like metastable oligomers, marking the beginning of the nucleation stage
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It is unclear whether nAbs in the sera reach the respiratory system, especially the lungs, to function
