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One route is the reductive amination of 2-oxoglutarate with ammonium as the nitrogen donor via glutamate dehydrogenase (GDH) (Fig

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Previous studies have applied the standard Mini-International Neuropsychiatric Interview or the Hamilton Depression Rating Scale and the Beck Depression Inventory for evaluating the mood state of GD patients, which can be potential methods for assessing the patients' mental state (182)

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