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This activation not only helps in neutralizing oxidative stress but also promotes cellular resilience against more significant stressors, thereby contributing to cancer chemoprevention and overall health maintenance

cDNA synthesis was performed using the High-Capacity Reverse Transcriptase Kit (Life Technologies) with random primers, following the manufacturers instructions for reactions without RNase inhibitor

However, about 1-2% of the electrons slip through complexes I and III of the ETC, after which they react with molecular oxygen to sequentially form ROS such as O 2 - , HO 2 and H 2 O 2 [5,11-13]

Two N-terminal deletion constructs lacking the 26 amino acid (aa) (Kozak-Chac1 (5)-Myc) and 226 aa (Kozak-Chac1 (25)-Myc) sequences of Chac1 were generated by PCR using pcDNA3.1-Kozak-Chac1-Myc as the template (Fig
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Some studies link low glutathione levels to metabolic dysfunction and obesity, suggesting supplementation could support metabolic health
