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In a previous study, we have reported that KEAP1 mutant tumors respond to CB-839 treatment, while growth of wild type tumors is unaffected in vivo (Romero et al., 2017)

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NagyCFLeachTSKingAGuttendorfR.Safety, pharmacokinetics, and immunogenicity of obiltoxaximab after intramuscular administration to healthy humans

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The D- form is completely inactive and in large quantities and particular conditions, the D- form may inhibit the utilization of L-carnitine

doi: 10.3390/ijms14036306