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[24] report that elevated collagen levels in the lungs of OVA-challenged C57BL/6 mice were reduced by anti-TNF- treatment

Additionally, AMPK also influences the transcription of specific genes involved in energy metabolism, thus exerting long-term metabolic control

Treatment depends on the cause and severity: oral supplementation suffices for dietary deficiency, whilst patients with pernicious anaemia or malabsorption typically require intramuscular hydroxocobalamin injections

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Its activity is mediated through copper transport, gene modulation, and interaction with extracellular matrix components