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These conditions can diminish the quality of life for older adults and impose a significant economic burden on families and society

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For example, one study showed that in people with type 2 diabetes, treatment with semaglutide (1 mg weekly) causes an average loss of about 6% of body weight over 40 weeks, while treatment with tirzepatide (15 mg/week) leads to an 11% weight loss in this population

Among typical behaviors assessed in mice and rats, directly related to the core symptoms of autism, are deficits in social interaction (i.e., three-chamber social approach paradigm), deficits in communication (i.e., analysis of ultrasonic vocalizations), increased repetitive/stereotyped motor behaviors (i.e., self-grooming or marble burying), and persistence on sameness and restricted interests (i.e., perseveration in the T maze or water maze) [23,24]