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Takahashi H, Yang G, Yoneshiro T, Abe Y, Ito R, Yang C, et al

Still, another orally administered synaptogenic small molecule SPG302, which is currently under clinical evaluation for amyotrophic lateral sclerosis (ALS, NCT05882695), has shown to reverse synaptic pathology and protects RGCs in a chronic OHT model, suggesting potential for future neuroprotective translation in glaucoma [201]

Researchers should avoid placing the vial in the coldest part of the refrigerator, such as directly against the back wall, where temperatures can fluctuate or dip low enough to affect solution stability

Ferritinophagy refers to the targeted autophagic degradation of FE, leading to the accumulation of cytoplasmic iron, primarily in the form of Fe 2+ 49

[17] Knockout studies with GPX1, GPX2, or GPX3 deficient mice showed that cytosolic GPX4 is so far the only glutathione peroxidase that is indispensable for embryonic development and cell survival

doi: 10.1016/j.jcmg.2022.07.006
