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In mitochondria it plays a key role in regulating apoptosis versus necrosis (see review by Yuan and Kaplowitz 2008 in this issue)
Similarly, chronic exposure to DON worsens inflammation, influencing gastrointestinal epithelial cells and immune responses [[91], [92], [93]]
Choi CH (2005) ABC transporters as multidrug resistance mechanisms and the development of chemosensitizers for their reversal
[Abstract] J Cachexia Sarcopenia Muscle
The duration of action of a drug, time to steady state levels, and time to washout are each influenced by the value of the drug half-life
