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(6)Fmoc-Asp(otBu)-Asp(otBu)-Ala-Gly-Leu-Val- (6) Preparation of Fmoc-Asp(otBu)-Asp(otBu)-Ala-Gly-Leu-Val-resin: (5)Fmoc-Asp(otBu)-Ala-Gly-Leu-Val-105053010501060 3DMF3DMF2DMFFmoc-Asp(otBu)-OHDIEATBTU/HOBtHBTU/HOBtBOP/HOBt105010603DMF3DMF2Fmoc-Asp(otBu)-Asp(otBu)-Ala-Gly-Leu-Val- In the Fmoc-Asp(otBu)-Ala-Gly-Leu-Val-resin in step (5), add the decapping reagent at 1050C for 530 minutes, dry it with a vacuum pump, and add the decapping reagent again at 1050C React for 10-60 minutes, drain, wash 3 times with isopropanol, 3 times with DMF, 2 times with distilled DMF, add Fmoc-Asp(otBu)-OH, DIEA, TBTU/HOBt dissolved in DMF Or the mixture of HBTU/HOBt or BOP/HOBt, react at 10-50C for 10-60 minutes, drain with a vacuum pump, wash with isopropanol for 3 times, wash with DMF for 3 times, wash with re-distilled DMF for 2 times, and drain , obtain Fmoc-Asp(otBu)-Asp(otBu)-Ala-Gly-Leu-Val-resin

HYGIENE A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS A61P27/00Drugs for disorders of the senses A61P27/02Ophthalmic agents AHUMAN NECESSITIES A61MEDICAL OR VETERINARY SCIENCE

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R.GrozioA.KubotaS.SasakiY.et al (2016)

SIH -: a novel lipophilic iron chelator -: protects H9c2 cardiomyoblasts from oxidative stress-induced mitochondrial injury and cell death

The results are summarised on the following two charts: Tests for pH-logS profile were also run