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in International Wound Journal

The solution still looks clear

(2) molecular dynamics simulated annealing restraining FOXO4 FH (without flexible regions) harmonically to its template structure (using a non-crystallographic force constant of 10,000 kcal mol 1 2 ), with additional dihedral angle restraints from 1 H, 15 N, and 13 C chemical shifts using TALOS-N 56 , hydrogen bond restraints (region p53 residues 48-55

Valenzano A, Tartaglia N, Ambrosi A, et al

4.2 Fruquintinib Fruquintinib is an orally available, highly selective small-molecule antagonist of VEGFR1, VEGFR2, and VEGFR3 (111)