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Splenectomy is sometimes of benefit

217 Autophagy-related proteins such as p62 and transcription factor EB (TFEB) are linked to GBM prognosis, with high p62 expression correlating with PS and tumor recurrence

The ensuing pathophysiology involves virus-induced neuronal damage, neuroinflammation, rupture of the BBB, microvasculitis and hypoxia 648

Contributing to the confusion was the common use of inadequate sample collection and processing procedures and methods of analysis of GSH and its various oxidation products in both laboratory and clinical studies