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Additionally, PERK inhibits SLC7A11 transcription via p53 upregulation, reducing cellular antioxidant capacity (Jiang et al
[DOI] [PubMed] [Google Scholar] 162.Alao, J
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doi: 10.1002/1521-4141(200104)31:4 3.0.CO;2-H, PMID: [DOI] [PMC free article] [PubMed] [Google Scholar] 119
The results provided evidence that cystine is a major regulator of cellular GSH metabolism which may contribute to cystine-induced cell signaling in HepG2 cells
Wang, X., McCullough, K
