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Powerful antioxidant: Contains glutathione, a powerful antioxidant that fights the destructive effects of UV radiation, free radicals and other environmental factors

Mechanistic Interpretation The study identifies a dual immunosuppressive role for IGF-1 in prostate cancer: Antigen presentation impairment: IGF-1 disrupts peptide transport and processing (via TAP1/2, ERAP1, 2M downregulation), reducing surface MHC-I expression and impairing CD8 T-cell recognition

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10.1128/MCB.26.8.2887-2900.2006 86 TsengC.-K.HsuS.-P.LinC.-K.WuY.-H.LeeJ.-C.YoungK.-C

[DOI] [PMC free article] [PubMed] [Google Scholar] 40.Gallagher C.S., Makinen N., Harris H.R., Rahmioglu N., Uimari O., Cook J.P., Shigesi N., Ferreira T., Velez-Edwards D.R., Edwards T.L., et al